The goal of this study is to evaluate the efficacy of the XStream Infection Control system against viruses, bacteria and spores from the air, surfaces and human hand transfers. Microbial surrogates will be used to represent human enteric and respiratory viruses (i.e. influenza and norovirus), MRSA and other bacterial pathogens, and C. difficile spores. The resulting data can be used for the development of exposure and risk assessment models for determining the relative risk reduction in human populations following XStream Infection Control system use.